Owen Dempsey

Company: Avipep Therapeutics

Job title: Chief Executive Officer

Seminars:

A Version of ADCs: Antibody Formats Amenable to Improving PK/PD of Radiopharmaceuticals 1:45 pm

Discussing differences in the mechanisms of action for an ADC versus radiopharmaceutical Exploring different antibody fragments to target and deliver radioactivity to the tumor and generate a good half-life locally Insights into novel click cleavable ADCs for delivery of radiotherapeuticsRead more

day: Day One - PM

AvDCs (Avibody Drug Conjugates): A Targeted Approach to Efficacy, Improved Tolerability & Favorable PK for Targeted Radio-Therapy, Novel ADC Formats, & Enhanced Tumor Selectivity 2:10 pm

Avibodies are engineered, bivalent mAb fragments, precisely loaded with radiotoxic or cytotoxic payloads Sharing pre-clinical data demonstrating traditional ADC, novel pre-targeting, and targeted radio therapy formats Biparatopic or bispecific designs against TSEs (Tumor Specific Epitopes) can further enhance solid tumor selectivityRead more

day: Day One - PM