Matthew Metzger
Seminars
Wednesday 10th September 2025
Opportunity to be First-in-Class: Considerations for Collaborations with New Targets
11:10 am
- What are the economics of having a new target for others to develop an ADC around?
- Discussing opportunities to be first-in-class pursuing underexploited targets
- Debating the decision to leverage the best linker-payload platform or off-patent technologies, considering the influence on the side effect profile
Wednesday 10th September 2025
ADC Deal-Making: Will Success Lead to More Success?
2:10 pm
- Discussing opportunity for and examples of creative deal structures across ADCs
- For payloads: Do you need the full ADC payload for a deal?
- For linkers: What drives deals with different types of linkers?
- For target discovery: What are the differences in deal structure versus linkers and payloads?
- Sharing guidance to progress from a research collaboration to a licensing agreement, and deal structure including direction for upfront milestones and royalties
